C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/381 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2756536
The present invention is related to novel thienopyrimidinedione derivatives as TRPA(Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/ or disorders modulated by TRPA1(Transient Receptor Potential subfamily A, member 1). Also provided herein are processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.
La présente invention concerne de nouveaux dérivés de thiénopyrimidinedione comme modulateurs de TRPA (Transient Receptor Potential, sous-famille A). En particulier, les composés décrits ici sont utiles pour traiter ou prévenir des maladies, des états et/ou des affections modulées par TRPA1 (Transient Receptor Potential, sous-famille A, membre 1). L'invention concerne également des procédés de préparation des composés décrits ici, des intermédiaires utilisés dans leur synthèse, des compositions pharmaceutiques les contenant et des méthodes de traitement ou de prévention de maladies, d'états et/ou d'affections modulés par TRPA1.
Khairatkar-Joshi Neelima
Kumar Sukeerthi
Margal Sanjay
Mukhopadhyay Indranil
Thomas Abraham
Glenmark Pharmaceuticals S.a.
Shapiro Cohen
LandOfFree
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