Thienopyrimidines for pharmaceutical compositions

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/381 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2735361

The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds ac-cording to formula (I). Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the in-hibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof wherein X is selected from CH or N.

La présente invention concerne de nouvelles compositions pharmaceutiques comprenant des composés de thiénopyrimidine selon la formule (I). De plus, la présente invention concerne lutilisation des composés de thiénopyrimidine de linvention pour la production de compositions pharmaceutiques pour la prophylaxie et/ou le traitement de maladies qui peuvent être influencées par linhibition de lactivité kinase de Mnk1 et/ou Mnk2 (Mnk2a ou Mnk2b) et/ou des variants de ceux-ci où X est choisi parmi CH ou N.

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