Thienopyrroles as antiviral agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 495/14 (2006.01) A61K 31/55 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2607421

The present invention relates to tetracyclic thienopyrrole compounds of formula (I), wherein Ar, A, D1, D2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.

La présente invention concerne des dérivés de thiénopyrrole tétracycliques de formule (I), où Ar, A, D1, D2, W, X, Y et Z sont tels que définis dans la présente invention, ainsi que des sels de qualité pharmaceutique desdits dérivés, les préparations pharmaceutiques les incluant, et leur application au traitement prophylactique ou thérapeutique d'une infection par le virus de l'hépatite C.

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