Thienoxazinone derivatives useful as antiviral agents

C - Chemistry – Metallurgy – 07 – D

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C07D 498/04 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2208458

Herpesvirus protease inhibitor 4H-thieno (2,3-d)(1,3) oxazin-4-one derivatives of formula (I) which are 2-substituted by X(Y)NH-CHR1 - wherein X is hydrogen or a blocking group, Y is an optionally present amino acid, and R1 is hydrogen or an amino acid side chain.

Dérivés 4H-thiéno (2,3-d)(1,3) oxazin-4-one, de la formule (I), agissant comme inhibiteurs de la protéase de l'herpèsvirus, et substitués par X(Y)NH-CHR¿1?-, où X représente hydrogène ou un groupe inhibiteur, Y représente un acide aminé éventuellement présent, et R¿1? représente hydrogène ou une chaîne latérale d'acide aminé.

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