Thienylazolylalcoxyethanamines, their preparation and their...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 409/06 (2006.01) A61K 31/38 (2006.01) A61K 31/4155 (2006.01) C07D 333/16 (2006.01)

Patent

CA 2328878

The thienylazolylalcoxyethanamines (I) wherein R1 is a hydrogen atom, a halogen or a lower alkyl radical; R2, R3 and R4 represent independently a hydrogen atom or a lower alkyl radical; and Az is a 5-member nitrogenated aromatic N-methyl substituted heterocycle which contains from one to three nitrogen atoms, have an analgesic activity in mammals, including human beings. The compounds (I) can be obtained for example by reacting a hydroxythienylazol derivative (IV) with a derivative of an appropriate N-(ethyl)amine. The compound (IV) are useful intermediates for the synthesis of the compounds (I). The compounds (I) can be applied to human and/or veterinary medicine.

L'invention concerne les thiénylazolylalcoxyéthanamines (I) où R1 représente un atome d'hydrogène, un halogène ou un radical alkyle inférieur, R2, R3 et R4 représentent indépendamment un atome d'hydrogène ou un radical alkyle inférieur et Az représente un hétérocycle aromatique azoté à 5 éléments, substitué par N-méthyle qui contient entre un et trois atome(s) d'azote. Les thiénylazolylalcoxyéthanamines présentent une activité analgésique chez les mammifères, y compris les humains. Les composés (I) peuvent être obtenus, par exemple, par réaction d'un dérivé d'hydroxythiénylazol (IV) avec un dérivé d'une N-(éthyl)amine adéquate. Les composés (IV) sont des intermédiaires utiles de synthèse des composés (I). Les composés (I) se trouvent une application en médecine humaine et/ou vétérinaire.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Thienylazolylalcoxyethanamines, their preparation and their... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thienylazolylalcoxyethanamines, their preparation and their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thienylazolylalcoxyethanamines, their preparation and their... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1792102

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.