Thio acid derived monocyclic n-heterocyclics as anticoagulants

Details Thio acid derived monocyclic n-heterocyclics as anticoagulants Thio acid derived monocyclic n-heterocyclics as anticoagulants

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/44 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2268172

This invention is directed to monocyclic N-heterocyclics which are substituted by acyclic or cyclic thio derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.

L'invention concerne des composés N-hétérocycliques monocycliques, substitués par des dérivés thio, acycliques ou cycliques, et utiles en tant qu'anticoagulants. Cette invention concerne également des compositions pharmaceutiques contenant les composés de l'invention ainsi que des procédés d'utilisation de ces composés pour traiter des états pathologiques caractérisés par une activité thrombotique.

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