Thioamide derivatives as progesterone receptor modulators

C - Chemistry – Metallurgy – 07 – D

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C07D 413/04 (2006.01) A61K 31/404 (2006.01) A61K 31/536 (2006.01) A61P 5/24 (2006.01) A61P 15/18 (2006.01) A61P 17/10 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2561014

Thioamide compounds, and specifically, thioamide pyrrole compounds, and preparation thereof are provided. These thioamide compounds can be used as progesterone receptor modulators, in contraception, and in the treatment of progesterone-related maladies (formula I).

La présente invention concerne des composés thioamide et plus spécifiquement des composés thioamide pyrrole ainsi que la préparation de ces derniers. Ces composés thioamide peuvent être utilisés en tant que modulateurs des récepteurs de la progestérone, pour la contraception et pour le traitement des maladies liées à la progestérone. Formule (I)

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