Thiocolchicoside analogues with myorelaxant and...

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 15/248 (2006.01) A61K 31/165 (2006.01) A61K 31/404 (2006.01) A61P 21/02 (2006.01) A61P 29/00 (2006.01) C07C 323/41 (2006.01)

Patent

CA 2615860

The present invention relates to 3-demethoxy-3-aminothiocolchicine glycosyl derivatives of general formula (I) in which R is hydrogen, methyl or hydroxymethyl. The compounds of formula (I) have myorelaxant and anti- inflammatory activity.

L'invention concerne des dérivés de 3-déméthoxy-3-aminothiocolchicine glycosyle représentés par la formule générale (I), dans laquelle R représente hydrogène, méthyle ou hydroxyméthyle. Les composés représentés par la formule (I) présentent une activité myorelaxante et anti-inflammatoire.

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