Thioformamide derivatives

Details Thioformamide derivatives Thioformamide derivatives

C - Chemistry, Metallurgy

07

D

167/179, 260/250

C07D 213/59 (2006.01) A61K 31/33 (2006.01) C07D 213/79 (2006.01) C07D 215/14 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2013470

- 83 - ABSTRACT Thioformamide derivatives of the formula (I) Image wherein R represents an alkyl group; A represents either:- (1) a phenyl group which is optionally substituted; or (2) a heteroaromatic group (e.g. pyrid-3-yl, quinolin-3-yl); Y represents:- an ethylene or methylene group or a direct bond; and B represents either:- a) a phenyl, pyridyl, furyl or thienyl group, each of which may be optionally substituted, or b) a straight- or branched-chain alkyl, alkenyl, or cycloalkyl group, each of which may be optionally substituted. These compounds may be formulated into pharmaceutical preparations and have utility in the treatment of disorders associated with smooth muscle contraction.

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