Thioketene derivatives and process for the preparation thereof

Details Thioketene derivatives and process for the preparation thereof Thioketene derivatives and process for the preparation thereof

C - Chemistry, Metallurgy

07

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167/208, 260/324

C07D 207/44 (2006.01) C07D 207/38 (2006.01) C07D 211/86 (2006.01) C07D 211/90 (2006.01) C07D 213/38 (2006.01) C07D 213/40 (2006.01) C07D 213/69 (2006.01) C07D 223/10 (2006.01) C07D 339/06 (2006.01) C07D 401/06 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01)

Patent

CA 1260466

- 77 - ABSTRACT OF DISCLOSURE Novel thioketene derivative of the formula: Image (I) wherein R1 is hydrogen atom, an alkyl group, a lower alkenyl group, a phenyl group or a group of the formula: -B-Y; Y is a nitrogen-containing monocyclic heterocyclic group or a substituted or unsubstituted phenyl group; B is a straight or branched lower alkylene group; R2 and R3 are both a lower alkyl group or combine together to form a group of the formula: -CH2CH2- or -CH=CH-; R4 is hydrogen atom, a lower alkyl group or a (lower alkoxy)carbonyl group; A is a group of the formula: -(CH2)n- or -CH(COOR5)-; n is an integer of 0, 1 or 2 and R5 is a lower alkyl group, are disclosed. Said compound (I) is useful as an agent for treating and protecting various liver diseases.

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