A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 39/04 (2006.01) A01N 25/32 (2006.01) A01N 31/02 (2006.01) A01N 37/36 (2006.01) A01N 37/44 (2006.01) A01N 37/46 (2006.01) A01N 43/40 (2006.01) A01N 47/34 (2006.01)
Patent
CA 2214136
Thiol compounds are employed in conjunction with compounds which modulate cell proliferation, both as to plants and mammals. The thiol compounds find effect in enhancing the effectiveness of auxin like compounds, either as herbicides or in enhancing root formation. In addition, thiol compounds act in conjunction with cytotoxic agents in mammals to allow for lower dosages of the cytotoxic agents while retaining the cytotoxic effect against hyperproliferative diseases, such as cancer. The combination finds particular effect against cells dependent upon an isoform of a surface membrane NADH oxidase for proliferation.
On utilise des composés de thiol en association avec des composés régulant la prolifération des cellules, aussi bien chez les végétaux que chez les mammifères. Les composés de thiol ont pour effet d'augmenter l'efficacité de composés tels que l'auxine, soit comme herbicides, soit comme stimulateurs de rhizogénèse. De plus, les composés de thiol, agissant en association avec des agents cytotoxiques chez les mammifères, rendent possible la réduction des doses d'agents cytotoxiques, tout en conservant l'effet cytotoxique contre les pathologies d'hyperprolifération, telles que le cancer. Cette association est particulièrement efficace contre les cellules dont la prolifération est commandée par un isoforme d'une NADH-oxydase d'une membrane de surface.
Mckay-Carey & Company
Purdue Research Foundation
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