Thiolated polypeptide compound derived from a tetanus toxin...

Details Thiolated polypeptide compound derived from a tetanus toxin... Thiolated polypeptide compound derived from a tetanus toxin...

C - Chemistry, Metallurgy

07

K

167/44, 530/15.1

C07K 19/00 (2006.01) A61K 39/385 (2006.01) A61K 47/48 (2006.01) C07D 213/71 (2006.01) C07K 14/33 (2006.01) C07K 14/34 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1152493

ABSTRACT OF THE DISCLOSURE The present invention relates to a new thiolated polypeptide compound derived from a fragment of tetanus toxin. This thiolated polypeptide compound is constituted by the B-IIb fragment of tetanus toxin to which at least one -SH group is directly or indirectly bound. Application : neuropharmacological retrograde axonal transport agent for transporting a medicine to the central nervous system.

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