C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/58 (2006.01) A61K 31/541 (2006.01) A61P 1/04 (2006.01) A61P 1/06 (2006.01) A61P 1/08 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) A61P 9/04 (2006.01) A61P 9/12 (2006.01) A61P 11/00 (2006.01) A61P 11/02 (2006.01) A61P 11/06 (2006.01) A61P 11/10 (2006.01) A61P 11/14 (2006.01) A61P 13/02 (2006.01) A61P 13/10 (2006.01) A61P 17/00 (2006.01) A61P 17/04 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 19/10 (2006.01) A61P 25/00 (2006.01) A61P 25/04 (2006.01) A61P 25/06 (2006.01) A61P 25/16 (2
Patent
CA 2620742
The present invention discloses a thiomorpholine compound represented by the formula [I]: wherein Ring A represents an optionally substituted benzene ring; Ring B represents an optionally substituted benzene ring; R1 represents hydrogen atom, an optionally substituted hydroxyl group, an optionally substituted amino group, an optionally substituted alkyl group, a substituted carbonyl group or a halogen atom; R2 represents hydrogen atom or an optionally substituted alkyl group; and R3a and R3b may be the same or different from each other, and each represent hydrogen atom or an optionally substituted alkyl group, or combined to each other at the both ends thereof to form an alkylene group, and n is an integer of 1 or 2, or a pharmaceutically acceptable salt thereof.
La présente invention concerne un composé de thiomorpholine représenté par la formule [I] : où le noyau A représente un noyau de benzène optionnellement substitué, le noyau B représente un anneau de benzène optionnellement substitué, R¿1? représente un atome d~hydrogène, un groupe d~hydroxyles optionnellement substitué, un groupe d~aminos optionnellement substitué, un groupe d~alkyles optionnellement substitué, un groupe de carbonyles optionnellement substitué ou un atome d~halogène, et R¿3a? et R¿3b? risquent d~être les mêmes ou différents l~un de l~autre et chacun représente un atome d~hydrogène ou un groupe d~alkyles optionnellement substitué ou combiné l~un à l~autre aux deux extrémités pour former un groupe d~alkylènes et n est un nombre entier de 1 ou 2 ou un sel en provenant pharmaceutiquement acceptable.
Miyake Tsutomu
Takahashi Masami
Yamanaka Takeshi
Mitsubishi Tanabe Pharma Corporation
Sim & Mcburney
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