Thiomorpholino steroid compounds, the use thereof for the...

C - Chemistry – Metallurgy – 07 – J

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C07J 43/00 (2006.01) A61K 31/58 (2006.01) A61P 15/08 (2006.01)

Patent

CA 2528904

The present invention relates to thiomorpholino steroid compounds of general formula (I), which may advantageously be employed to stimulate meiosis in human oocytes, the steroid being specifically characterized by a thiomorpholino moiety bonded to C17 of the steroid skeleton via an alkylen spacer.

L'invention concerne des composés thiomorpholino stéroïdes de formule I, qui peuvent être utilisés, de manière avantageuse, pour stimuler la méiose dans des ovocytes, les stéroïdes se caractérisant de manière spécifique par une fraction thiomorpholino liée à C?17¿ du squelette du stéroïde par l'intermédiaire d'un espaceur alkylène.

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