C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/097 (2006.01) A61K 38/00 (2006.01) A61P 31/04 (2006.01) C07K 5/078 (2006.01) C12P 17/18 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2440353
A microorganism belonging to the genus Bacillus is cultured and novel thiopeptide compounds QN3323 and publicly known compounds thiocillin I/II, etc. are collected from the culture medium. Because of having a favorable antibacterial activity, these thiopeptide compounds are useful as drugs, in particular, remedies for infection with multidrug-resistant bacteria.
Selon l'invention, la culture d'un micro-organisme appartenant au genre <i>Bacillus</i> permet de récolter des composés thiopeptides QN3323 et des composés thiocillines I/II connus. En raison d'une activité antibactérienne favorable, ces composés thiopeptides sont utiles en tant que médicaments, en particulier en tant que remèdes pour des infections dues à des bactéries multirésistantes.
Arao Nakako
Kamigiri Kazuma
Kawano Yasuhiro
Kurane Ryuichiro
Nagai Koji
Astellas Pharma Inc.
Dennison Associates
National Institute Of Advanced Industrial Science And Technology
Yamanouchi Pharmaceutical Co. Ltd.
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