C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/12 (2006.01) A61K 31/381 (2006.01) A61K 31/4196 (2006.01) A61K 31/4535 (2006.01) A61K 31/7056 (2006.01) A61K 38/21 (2006.01) A61P 31/14 (2006.01) C07D 333/40 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2670260
The present invention relates to compounds represented by formula IA or pharmaceutically acceptable salts and solvates thereof which are useful for treating flaviviridae viral infections wherein R1 is C1-6 alkyl or C3-6 cycloalkyl; X is M is R5 is cyclohexyl which is unsubstituted or substituted one or more times by R13; R6 is or cyclohexyl which is substituted in the 4 position by R14; and Y, R14a and R14 are as defined herein.
La présente invention concerne des composés représentés par la formule IA ou leurs sels ou solvates acceptables du point de vue pharmaceutique, qui sont utiles pour traiter des infections virales de flaviviridae. Dans la formule IA, R1 est alkyle en C1-6 ou cycloalkyle en C3-6; X est M et R5 est un cyclohexyle qui est non substitué ou substitué une ou plusieurs fois par R13 ; R6 est un cyclohexyle qui est substitué en position 4 par R14 ; et Y, R14a et R14 sont tels que définis présentement.
Chan Chun Kong Laval
Das Sanjoy Kumar
Denis Real
Falardeau Guy
Poisson Carl
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Virochem Pharma Inc.
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