C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/00 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01) C07D 471/20 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2093516
ABSTRACT Thiophene compounds of the formula Image (I) wherein each symbol is as defined in the specification, their pharmaceutically acceptable salts, pharmaceutical compositions containing said compound and additives for pharmaceuticals, and antipsychotics containing said compound as an active ingredient. The compound of the present invention has pharmacological actions required of antipsychotic, such as motility suppressing action, anti-apomorphine action, methamphetamine antagonistic action, tetrabenazine-induced blepharoptosis enhancing action, and the like. The compound of the present invention is useful as an antipsychotic having less extrapyramidal side-effects or a non-benzodiazepine type antianxiety agent. 77
Morimoto Yasuto
Nakao Tohru
Obata Minoru
Ono Yuji
Tanaka Hiroshi
Fetherstonhaugh & Co.
Yoshitomi Pharmaceutical Industries Ltd.
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