Thiophene compounds for inflammation and immune-related uses

Details Thiophene compounds for inflammation and immune-related uses Thiophene compounds for inflammation and immune-related uses

C - Chemistry, Metallurgy

07

D

C07D 333/10 (2006.01)

Patent

CA 2595000

The invention relates to compounds of structural formulas (I) and (XVI) or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein X1, X2, Z, L, L2, R1, R2, R3, R21, n, q, and t are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

La présente invention concerne des composés représentés par les formules (I) et (XVI) ou un sel pharmaceutiquement acceptable, un solvate, un clathrate ou un promédicament de ce dernier. Dans les formules, X1, X2, Z, L, L2, R1, R2, R3, R21, n, q et t sont tels que définis dans le descriptif. Ces composés sont utiles en tant qu'agents immunosuppresseurs et pour traiter et prévenir les états inflammatoires, les troubles allergiques et les troubles immunitaires.

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