Thiophene derivatives

Details Thiophene derivatives Thiophene derivatives

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/407 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2761845

Compounds of formula (I), preparation method thereof and pharmaceutical compositions containing such compounds are disclosed, wherein R1, R2, R3, R4, R5, R6, R7 and R8 are defined in the description. The uses of said compounds for manufacturing a medicament for the treatment of PDE4-mediated diseases or conditions are also disclosed.

La présente invention concerne des composés de formule (I), dans laquelle: R1, R2, R3, R4, R5, R6, R7 et R8 sont tels que définis dans la description, leur procédé de préparation et des compositions pharmaceutiques contenant de tels composés. L'invention concerne également les utilisations desdits composés pour le traitement de maladies et de conditions liées à la PDE4.

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