C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 333/38 (2006.01) A61K 31/38 (2006.01) A61P 3/00 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2622334
The invention is concerned with novel substituted thiophene derivatives of formula (I), wherein R1 to R8, X, m and n are as defined in the description and in the claims, as well as 5 physiologically acceptable salts and esters thereof. These compounds are HM74A agonists and can be used as medicaments.
La présente invention concerne de nouveaux dérivés substitués du thiophène de formule (I) où R1 à R8, X, m et n sont tels que définis dans la description et dans les revendications, de même que 5 sels et esters de qualité physiologique desdits composés. Ces composés sont des antagonistes de HM74A et peuvent être employés en tant que médicaments.
Dehmlow Henrietta
Grether Uwe
Kratochwil Nicole A.
Narquizian Robert
Panousis Constantinos G.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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