Thiophene-ethyl thiourea compounds and use in the treatment...

Details Thiophene-ethyl thiourea compounds and use in the treatment... Thiophene-ethyl thiourea compounds and use in the treatment...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/427 (2006.01) A61K 31/4436 (2006.01) A61P 31/18 (2006.01) C07D 213/75 (2006.01) C07D 333/20 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2375261

Novel thiophene-ethyl-thiourea (TET) compounds as inhibitors of reverse transcriptase and effective agents for the treatment of HIV infection, including mutant, drug-sentitive, drug-resistant, and multi-drug resistant strains of HIV.

L'invention porte sur de nouveaux composés de thiophène-éthyl thio-urée (TET) agissant comme inhibiteurs de la transcriptase inverse, et s'avérant des agents efficaces dans le traitement de l'infection par le VIH, y compris par ses souches mutantes, sensibles aux médicaments, résistant aux médicaments, et résistant aux plurithérapies.

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