Thiophene or thiazole derivatives and their use as pi3k...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 409/04 (2006.01) A61K 31/4196 (2006.01) A61K 31/427 (2006.01) A61K 31/5377 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 409/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2727069

This invention provides compounds of formula (I) wherein R1, R2, CY, Y1, Y2, X1, X2, and X3 are as described in the specification. The compounds are inhibitors of PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

La présente invention concerne des composés représentés par la formule (I) dans laquelle R1, R2, CY, Y1, Y2, X1, X2, et X3 sont tels que décrits dans la spécification. Ces composés, qui sont des inhibiteurs de PI3K, conviennent pour le traitement de troubles proliférants, inflammatoires ou cardiovasculaires.

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