Thiotungstate analogues and uses thereof

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

C07F 11/00 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2527236

The current invention provides novel thiotungstate derivatives, methods of making novel thiotungstate derivatives, pharmaceutical compositions of novel thiotungstate derivatives, methods of using novel thiotungstate derivatives to treat diseases associated with aberrant vascularization, copper metabolism disorders and obesity and methods of using pharmaceutical compositions of thiotungstate derivatives to treat diseases associated with aberrant vascularization, copper metabolism disorders, neurodegenerative disorders, obesity or NF-kB dysregulation.

La présente invention concerne de nouveaux dérivés de thiotungstate, des procédés de production de nouveaux dérivés de thiotungstate, des compositions pharmaceutiques contenant les nouveaux dérivés de thiotungstate, des procédés d'utilisation des nouveaux dérivés de thiotungstate pour traiter des états associés à une vascularisation aberrante, des troubles du métabolisme du cuivre ainsi que l'obésité et des procédés d'utilisation de compositions pharmaceutiques contenant des dérivés de thiotungstate pour traiter des maladies associées à une vascularisation aberrante, des troubles du métabolisme du cuivre, des troubles neurodégénératifs, l'obésité ou un dysfonctionnement NF-.kappa.B.

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