Thiourea and isothiourea derivatives for inhibiting...

Details Thiourea and isothiourea derivatives for inhibiting... Thiourea and isothiourea derivatives for inhibiting...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/41 (2006.01) C07D 231/12 (2006.01) C07D 233/56 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2380371

The present invention relates to thiourea and isothiourea derivatives of formula (I) or pharmaceutically acceptable salt thereof which possess excellent activity for inhibiting ras-transformed cell growth wherein, A, B, R1, R2, R3, R4, R5 and R6 have the same meaning as defined in the specification.

L'invention porte sur des dérivés du thiourée et de l'isothiourée de formule (I) ou leurs sels pharmacocompatibles présentant une excellente capacité d'inhibition de la croissance de cellules transformées par le RAS. Dans la formule (I) A, B, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ ont la même signification que dans la description.

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