Thioxanthenone antitumor agents

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 335/16 (2006.01) A61K 31/38 (2006.01)

Patent

CA 2070799

1-[[(Dialkylamino)alkyl]amino]-4-substituted-thioxanthen-9- ones of the formula I Image (wherein n is 2 or 3; R1, R2 and R3 are lower alkyl; and R4 is hydrogen, lower alkyl, lower alkoxy or halogen) are disclosed as antitumor agents. Compositions containing the thioxanthenones and methods of treating tumors and cancer in mammals with the thioxanthenones are also disclosed.

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