Thioxanthine derivatives as myeloperoxidase inhibitors

Details Thioxanthine derivatives as myeloperoxidase inhibitors Thioxanthine derivatives as myeloperoxidase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 473/36 (2006.01) A61K 31/52 (2006.01)

Patent

CA 2752132

There is disclosed the use of a compound of formula (Ia) or (Ib) wherein R1, R2, R3, R4, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of the enzyme myeloperoxidase (MPO) is beneficial. Certain novel compounds of formula (Ia) or (Ib) and pharmaceutically acceptable salts thereof are disclosed, together with processes for their preparation. The compounds of formulae (Ia) and (Ib) are MPO inhibitors and are thereby particularly useful in the treatment or prophylaxis of neuroinflammatory disorders. (see formula Ia) (see formula Ib)

Affiliated with

Also associated with

Rating

Thioxanthine derivatives as myeloperoxidase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thioxanthine derivatives as myeloperoxidase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thioxanthine derivatives as myeloperoxidase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1919532