Thorium or actinium radionuclides for endoradionuclide therapy

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01)

Patent

CA 2413736

The invention provides a method of radiation treatment of a human or non-human mammalian subject which comprises administering to said subject a therapeutically, prophylactically or pain-palliating amount of a bone- targeting complex of an alpha-particle emitting thorium or actinium radionuclide, e.g. for the treatment of calcified tumors, bone tumors, bones, bone surfaces an soft tissues.

L'invention concerne un procédé de traitement par radiation d'un sujet humain ou d'un mammifère. Ce procédé comprend l'administration audit sujet ou mammifère d'une quantité d'un complexe thérapeutique, prophylactique ou palliatif d'atténuation de la douleur, ciblant les os, d'un radionucléïde de thorium ou d'actinium émettant des particules alpha, par exemple pour le traitement de tumeurs calcifiées, de tumeurs osseuses, d'os, de surfaces osseuses et de tissus mous.

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