Three-dimensional microfluidic devices

G - Physics – 01 – N

Patent

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G01N 35/00 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2719320

Three-dimensional microfluidic devices including by a plurality of patterned porous, hydrophilic layers and a fluid-impermeable layer disposed between every two adjacent patterned porous, hydrophilic layers are described. Each patterned porous, hydrophilic layer has a fluid-impermeable barrier which substantially permeates the thickness of the porous, hydrophilic layer and defines boundaries of one or more hydrophilic regions within the patterned porous, hydrophilic layer. The fluid-impermeable layer has openings which are aligned with at least part of the hydrophilic region within at least one adjacent patterned porous, hydrophilic layer. Microfluidic assay device, microfluidic mixer, microfluidic flow control device are also described.

Dispositifs microfluidiques tridimensionnels comprenant une pluralité de couches hydrophiles poreuses texturées et une couche imperméable aux fluides disposée entre deux couches hydrophiles poreuses texturées adjacentes. Chaque couche hydrophile poreuse texturée a une barrière imperméable aux fluides qui traverse pratiquement l'épaisseur de cette couche hydrophile poreuse texturée et définit les frontières d'une ou de plusieurs régions hydrophiles à l'intérieur de cette couche hydrophile poreuse texturée. La couche imperméable aux fluides a des ouvertures qui sont alignées avec au moins une partie de la région hydrophile dans au moins une couche hydrophile poreuse texturée adjacente. L'invention concerne également un dispositif d'analyse microfluidique et un dispositif de régulation de flux microfluidique.

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