Three-dimensional skin model

Details Three-dimensional skin model Three-dimensional skin model

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61K 35/36 (2006.01) A61L 27/24 (2006.01) A61L 27/38 (2006.01) A61L 27/60 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2410956

The invention relates to methods for cultivating dermal fibroblasts, methods for producing in vitro dermis equivalents, methods for producing three- dimensional in vitro skin equivalents, an in vitro dermis equivalent, a three- dimensional in vitro skin equivalent and methods for determining the effect of a chemical substances or an agent on human skin cells using the in vitro dermis equivalent and/or the in vitro skin equivalent.

L'invention concerne un procédé de culture de fibroblastes dermiques, un procédé de préparation d'équivalents de derme in vitro, un procédé de préparation d'équivalents de peau in vitro tridimensionnels, un équivalent de derme in vitro, un équivalent de peau in vitro tridimensionnel, ainsi qu'un procédé de détermination de l'action d'une substance chimique ou d'un agent sur des cellules de peau humaines, ledit procédé utilisant l'équivalent de derme in vitro et/ou l'équivalent de peau in vitro.

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