Thrombin inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 413/06 (2006.01) C07K 5/02 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2283704

A compound which inhibits human thrombin and has structure (I) or (II) or (III) and pharmaceutically acceptable salts thereof, wherein compounds such as (IV) are useful for inhibiting formation of blood platelet aggregates in blood in a mammal.

L'invention concerne un composé inhibant la thrombine humaine et ayant la structure (I) ou (II) ou (III), ainsi que des sels pharmaceutiquement acceptables dudit composé (IV), caractérisé en ce que des composés tels que sont utiles pour inhiber la formation d'agrégats de plaquettes dans le sang d'un mammifère.

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