Thrombin inhibitors

Details Thrombin inhibitors Thrombin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 498/04 (2006.01) A61K 31/5365 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2369109

Compounds of the invention, useful as thrombin inhibitors and having therapeutic value in for example, preventing coronary artery disease, have structure: (I) or a pharmaceutically acceptable salt thereof, wherein A is (a), (b), (c), (d), or (e).

Les composés de cette invention, utiles en tant qu'inhibiteurs de la thrombine et possédant une valeur thérapeutique dans, par ex., la prévention de maladie coronarienne, présentent la structure: (I) ou un sel correspondant valide sur le plan pharmaceutique, où A représente (a) ou (b), (c), (d), ou (e).

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