Thrombin or factor xa inhibitors

Details Thrombin or factor xa inhibitors Thrombin or factor xa inhibitors

C - Chemistry, Metallurgy

07

D

C07D 253/02 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) A61P 9/00 (2006.01) C07D 213/74 (2006.01) C07D 221/04 (2006.01) C07D 257/02 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 491/02 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 498/02 (2006.01)

Patent

CA 2349557

This invention relates generally to inhibitors of trypsin-like serine protease enzymes, especially factor Xa or thrombin, pharmaceutical compositions containing the same, and methods of using the same as anticoagulant agents for treatment and prevention of thromboembolic disorders.

L'invention concerne de façon générale des inhibiteurs d'enzymes sérine protéase semblables à trypsine, en particulier le facteur Xa ou thrombine, des compositions pharmaceutiques les contenant, ainsi que des procédés servant à les mettre en application en tant qu'agents anticoagulants pour le traitement et la prévention d'embolies provoquées par une thrombose.

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