Thrombin or factor xa inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/495 (2006.01) C07D 213/74 (2006.01) C07D 221/04 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 487/02 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2320730

This invention relates generally to inhibitors of trypsin-like serine protease enzymes, especially factor Xa or thrombin, pharmaceutical compositions containing the same, and methods of using the same as anticoagulant agents for treatment and prevention of thromboembolic disorders.

L'invention concerne d'une manière générale des inhibiteurs des sérines protéases apparentées à la trypsine, notamment le facteur Xa ou la thrombine. Elle porte également sur des compositions pharmaceutiques contenant lesdits inhibiteurs et sur des méthodes d'utilisation de ces derniers comme agents anticoagulants pour le traitement et la prévention de troubles thromboemboliques.

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