C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/46 (2006.01) A61K 31/655 (2006.01) A61P 7/02 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2411468
Invented are non-peptide TPO mimetics. Also invented are novel processes and intermediates used in the preparation of the presently invented compounds. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
L'invention concerne des mimiques de TPO non peptidique, ainsi que de nouveaux procédés et intermédiaires utilisés dans la préparation desdits composés. L'invention concerne par ailleurs un procédé permettant de traiter la thrombocytopénie chez des mammifères, y compris chez l'humain, selon lequel il est prévu d'administrer aux mammifères concernés une dose efficace d'un dérivé sélectionné d'hydroxy-1-azobenzène.
Duffy Kevin J.
Eppley Daniel F.
Erickson-Miller Connie L.
Jenkins Julian
Liu Nannan
Glaxo Group Limited
Glaxosmithkline Llc
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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