C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 337/08 (2006.01) A61K 31/175 (2006.01) A61K 31/192 (2006.01) A61K 31/415 (2006.01) A61P 7/00 (2006.01) C07C 281/00 (2006.01) C07D 231/20 (2006.01)
Patent
CA 2436288
Invented are non-peptide TPO mimetics. also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected substituted thiosemicarbazone derivative.
L'invention concerne des mimétiques de thrombopoiétine non peptidiques. L'invention concerne par ailleurs un procédé de traitement de thrombocytopénie chez un mamifère, y compris chez l'homme, consistant à administrer audit mammifère une quantité efficace d'un dérivé de thiosémicarbazone substitué choisi.
Duffy Kevin J.
Jenkins Julian
Luengo Juan I.
Miller Stephen G.
Price Alan T.
Gowling Lafleur Henderson Llp
Ligand Pharmaceuticals
Smithkline Beecham Corporation
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