Thrombosis filter having a surface treatment

Details Thrombosis filter having a surface treatment Thrombosis filter having a surface treatment

A - Human Necessities

61

L

A61L 27/54 (2006.01) A61F 2/01 (2006.01) A61L 27/04 (2006.01) A61L 27/14 (2006.01) A61L 27/18 (2006.01) A61L 27/58 (2006.01) A61K 31/337 (2006.01)

Patent

CA 2378977

A thrombosis filter configured for placement within a blood vessel lumen. The thrombosis filter of the present invention includes a body element, a plurality of struts, and a surface treatment. The surface treatment, comprised in part of an anti-proliferative or anti-angiogenic drug, is applied to portions of the thrombosis filter in order to regulate neointimal growth around the thrombosis filter and its anchor elements. The thrombosis filter may further contain a first and a second surface treatment layer. The first surface treatment layer possesses endothelial cell growth enhancing properties, while the second surface treatment layer includes the anti-proliferative or anti-angiogenic drug. The surface treatment may alternatively be applied to a substrate, which in turn is applied to the filter.

Ce filtre thrombotique est conçu pour être placé dans la lumière d'un vaisseau sanguin et il comprend un corps et plusieurs supports et sa surface est dotée d'un traitement. Ce traitement de surface, composé en parti d'un médicament anti-prolifératif ou anti-angiogénique, est appliqué sur des portions du filtre thrombotique de manière à réguler la croissance néo-intimale autour du filtre et des éléments d'ancrage de celui-ci. Ce filtre peut comporter une première et une seconde couche de traitement de surface, la première possédant des propriétés favorisant la croissance des cellules endothéliales, tandis que la seconde comprend le médicament anti-prolifératif ou anti-angiogénique. Dans un autre mode de réalisation, on peut appliquer le traitement sur un substrat que l'on applique ensuite sur le filtre.

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