Thymic stromal lymphopoietin (tslp) antibodies and uses thereof

Details Thymic stromal lymphopoietin (tslp) antibodies and uses thereof Thymic stromal lymphopoietin (tslp) antibodies and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2638851

The present invention relates to human thymic stromal lymphopoietin (hTSLP) antibodies and especially those which neutralize hTSLP activity. It further relates to methods for using anti- hTSLP antibody molecules in diagnosis or treatment of hTSLP related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.

La présente invention concerne des anticorps de la lymphopoïétine stromale thymique humaine (hTSLP), notamment ceux qui neutralisent l'activité de hTSLP. L'invention concerne également des procédés d'utilisation des molécules d'anticorps anti-hTSLP pour le diagnostic ou le traitement de troubles liés à hTSLP, tels que l'asthme, la dermatite atopique, la rhinite allergique, la fibrose, l'affection abdominale inflammatoire et le lymphome de Hodgkin.

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