Thymidine kinase

Details Thymidine kinase Thymidine kinase

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2569304

A polynucleotide comprising a nucleotide sequence encoding a thymidine kinase wherein at least one of the nucleotides corresponding to the splice donor site nucleotides is replaced by another nucleotide and wherein the nucleotides of the splice acceptor sites are not altered.

L'invention concerne un polynucléotide comprenant une séquence nucléotidique codant pour une thymidine kinase. Au moins l'un des nucléotides correspondant aux nucléotides du donneur d'épissage est remplacé par un autre nucléotide et les nucléotides des accepteurs d'épissage ne sont pas modifiés.

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