Thyroid receptor agonists

Details Thyroid receptor agonists Thyroid receptor agonists

A - Human Necessities

61

K

A61K 31/192 (2006.01) C07C 59/64 (2006.01)

Patent

CA 2562633

The invention provides compounds of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition mediated by a thyroid receptor. Formula (I), wherein R1, R2, n, Y, Y', R3, R4, W and R5 are as defined in the specification.

L'invention concerne des composés représentés par la formule générale (I) ou un ester, un amide, un solvate ou un sel de qualité pharmaceutique de ces composés, y compris un sel d'un de ces ester ou amide et un solvate d'un de ces ester, amide ou sel. L'invention concerne également l'utilisation de ces composés pour le traitement ou la prévention d'un trouble induit par un récepteur thyroïdien. Dans la formule générale (I), R?1¿, R?2¿, n, Y, Y', R?3¿, R?4¿, W et R?5¿ désignent des éléments définis dans la description.

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