Tiacumicin production

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 19/62 (2006.01) C07H 17/08 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2494742

Methods, processes and materials for the production and recovery of Tiacumicins produced by culturing a microorganism belonging to the species Dactylosporangium aurantiacum subspecies hamdenensis having the ability to produce and accumulate one or more Tiacumicin in a nutrient medium comprising a carbon source, a nitrogen source, trace elements such as inorganic salts, and an adsorbent, wherein said nitrogen source comprises fish powder, and wherein said Tiacumicin is produced in a yield greater than about 50 mg/L broth.

L'invention concerne des méthodes, des procédés et des matériaux de fabrication et de récupération de Tiacumicines fabriquées par culture d'un micro-organisme appartenant aux espèces Dactylosporangium aurantiacum et aux sous-espèces hamdenensis ayant la capacité de fabriquer et d'accumuler au moins une Tiacumicine dans un milieu nutritif contenant une source de carbone, une source d'azote, des éléments traces tels que des sels inorganiques, et un adsorbant, la source d'azote contenant de la poudre de poisson, et la Tiacumicine étant fabriquée dans une quantité supérieure à environ 50 mg/L de bouillon.

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