Time-lapse cell cycle analysis of unstained nuclei

Details Time-lapse cell cycle analysis of unstained nuclei Time-lapse cell cycle analysis of unstained nuclei

G - Physics

06

T

G06T 7/20 (2006.01) G06T 5/00 (2006.01)

Patent

CA 2629349

The present invention provides a cell imaging technique for automatically tracking the progression of a cell through the cell cycle over time through segmentation of a volume of two-dimensional time-lapse images. The technique allows long-term tracking of the cell cycle progression of an individual cell or multiple cells. Further, the invention provides a unique display of cell cycle progression, allowing an end user to easily determine changes to cell cycle progression for a cell of interest.

L'invention concerne une technique d'imagerie cellulaire qui permet de suivre automatiquement la progression d'une cellule dans le cycle cellulaire au fil du temps par segmentation d'un volume d'images bidimensionnelles à intervalles. Cette technique permet d'assurer un suivi à long terme de la progression du cycle cellulaire d'une cellule individuelle ou de plusieurs cellules. L'invention propose également un affichage unique d'une progression de cycle cellulaire, ce qui permet à un utilisateur final de déterminer des changements apportés à la progression du cycle cellulaire d'une cellule d'intérêt.

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