C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/18 (2006.01)
Patent
CA 2531718
The present invention relates to a multi-well assay for identifying a compound inhibiting the replication cycle of a micro-organism, for example, HIV, and to an apparatus for carrying out an assay according to the present invention. The invention further relates to compounds identifiable with an assay according to the invention and pharmaceutical compositions comprising a therapeutically effective amount of such compounds. The identified compounds may be used as medicaments, and in particular for the manufacture of a medicament for treating infectious diseases and in method for treating infectious diseases including AIDS.
L'invention se rapporte à une analyse faisant appel à des puits multiples pour identifier un composé inhibant le cycle de réplication d'un micro-organisme, par exemple du VIH, ainsi qu'à un appareil servant à effectuer cette analyse. La présente invention concerne également des composés identifiables au moyen d'une analyse selon l'invention, ainsi que des compositions pharmaceutiques qui comprennent une dose thérapeutiquement efficace desdits composés. Les composés identifiés peuvent être utilisés en tant que médicaments, en particulier pour produire un médicament destiné à traiter des maladies infectieuses. L'invention se rapporte par ailleurs à un procédé pour traiter des maladies infectieuses parmi lesquelles figurent le SIDA.
Bunkens Lieve Elisabeth Louis
Dams Gery Karel Julia
Hertogs Kurt
Ivens Tania Pauline Eduard
Nijs Erik Jos Amandus
Gowling Lafleur Henderson Llp
Tibotec Pharmaceuticals Ltd.
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