Timed dual release dosage forms comprising a short acting...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/50 (2006.01) A61K 9/00 (2006.01) A61K 31/437 (2006.01) A61P 25/20 (2006.01)

Patent

CA 2370556

The present invention relates to timed dual release dosage forms of short acting hypnotics or salts thereof adapted to release the short acting hypnotic over a predetermined time period, according to a profile of dissolution characterised in that it comprises two release pulses, the first being immediate (lasting up to 30 minutes) and the second being delayed by a fixed time (this fixed time being between 50 and 200 minutes).

La présente invention concerne des formes de dosage à double libération dans le temps d'hypnotiques, ou de leurs sels, à action brève conçus afin de libérer l'hypnotique à action brève durant une période de temps prédéterminée, selon un profil de dissolution caractérisé en ce que ce profil comporte deux impulsions de libération, la première étant immédiate (durant jusqu'à 30 minutes) et la seconde différée d'un intervalle fixe de temps (cet intervalle fixe étant compris entre 50 et 200 minutes).

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