Tiotropium bromide having a low degree of crystallinity

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 491/08 (2006.01) A61K 31/46 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2742356

The present invention provides tiotropium bromide having a low degree of crystallinity. The present invention also provides a complex of tiotropium bromide and polyvinylpyrrolidone, processes for preparing it and pharmaceutical formulations including it.

La présente invention concerne du bromure de tiotropium ayant un faible degré de cristallinité. La présente invention concerne également un complexe de bromure de tiotropium et de polyvinylpyrrolidone, des procédés pour sa préparation et des préparations pharmaceutiques le contenant.

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