Tissue adhesive for treating vigorously bleeding surfaces

A - Human Necessities – 61 – L

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61L 17/14 (2006.01) A61L 24/00 (2006.01) A61L 24/04 (2006.01) A61L 24/10 (2006.01) A61L 26/00 (2006.01)

Patent

CA 2358567

Disclosed is a novel tissue adhesive technology comprising a combination of ultrasonically treated proteins including collagen and albumin which form a viscous material that develops adhesive properties when chemically cross- linked. A novel new cross-linking agent with surprisingly stable properties was developed in association with the tissue adhesive described and claimed herein and is considered to be within the scope of the present invention. This new cross-linking agent is a product of reaction glutaraldehyde with amino acids or peptides and allowing the reacting to proceed to completion. This chemical cross-linking is mixed with the ultrasonically treated proteins, allowed to react for a predetermined time, then used to seal large surface areas of vigorously bleeding tissues including, but not limited to, the liver, lungs and major vascular systems in patients with and without bleeding disorders. This same tissue adhesive has proven to work well in sealing suture sites to prevent leakage.

L'invention concerne une nouvelle technologie d'adhésif tissulaire consistant en une combinaison de protéines traitées par ultrasons et comprenant du collagène et de l'albumine formant une matière visqueuse qui développe des propriétés adhésives lorsqu'elle est réticulée chimiquement. L'invention concerne également un nouvel agent de réticulation développée en association avec ledit adhésif tissulaire et doté de propriétés étonnamment stables obtenu en faisant réagir du glutaraldéhyde avec des peptides ou des acides aminés et en laissant cette réaction arriver à terme. On mélange ensuite cet agent de réticulation chimique à ces protéines traitées par ultrasons, on le fait réagir pendant une durée prédéterminée, puis on l'utilise pour fermer hermétiquement de larges surfaces de tissus saignant abondamment, y compris notamment le foie, les poumons et les systèmes vasculaires majeurs, chez des sujets souffrant ou ne souffrant pas des troubles de saignement. Il a été avéré que ledit adhésif tissulaire convient pour fermer des sites de suture et permet d'empêcher toute fuite.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Tissue adhesive for treating vigorously bleeding surfaces does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tissue adhesive for treating vigorously bleeding surfaces, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tissue adhesive for treating vigorously bleeding surfaces will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1840184

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.