A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/04 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61L 31/16 (2006.01) A61L 31/18 (2006.01) C08F 8/00 (2006.01) C08J 3/075 (2006.01) C08J 3/24 (2006.01) C08L 29/04 (2006.01) C08L 101/06 (2006.01) C09D 129/04 (2006.01) C09D 201/06 (2006.01)
Patent
CA 2402773
Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and hydrolyzed copolymers of vinyl acetate, for example, copolymers with vinyl chloride, N-vinylpyrrolidone, etc. The backbone polymer contains pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as agents to bulk and coat tissues.
Cette invention concerne des compositions renfermant des macromères dont le squelette compte des unités à structure 1,2-diol et/ou 1,3-diol pour le revêtement et le gonflement de tissus. Ces polymères comprennent un poly(alcool de vinyle) et des copolymères hydrolisés d'acétate de vinyle, tels que des copolymères avec chlorure de vinyle, N-vinylpyrrolidone, etc. Le polymère squelette renferme des chaînes portant des groupes réticulables et, éventuellement, d'autres modificateurs. Lorsqu'ils sont réticulés, les macromères forment des hydrogels possédant maintes propriétés qui en font des agents utiles pour le gonflement et le revêtement de tissus.
Asfaw Bruktawit T.
Chaouk Hassan
Goodrich Stephen D.
Goupil Dennis W.
Holland Troy
Biocompatibles Uk Limited
Biocure Inc.
Fetherstonhaugh & Co.
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