Tissue-derived tumor growth inhibitors, methods of...

Details Tissue-derived tumor growth inhibitors, methods of... Tissue-derived tumor growth inhibitors, methods of...

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 35/28 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) C07K 14/495 (2006.01) C07K 16/22 (2006.01) C12N 5/02 (2006.01) C12N 5/08 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2084510

2084510 9200330 PCTABS00010 The present invention provides (1) an antibody which (a) specifically binds to human TGF-.beta.3 and (b) exhibits substantially no cross reactivity with TGF-.beta.1 or TGF-.beta.2 and (2) antibodies directed against the pro region of the TGF-.beta. precursor. Further, this invention provides a pharmaceutical composition comprising the pro region of the TGF-.beta. precursor. Also, this invention provides methods for diagnosing, detecting and treating subjects suffering form disorders associated with TGF-.beta.3.

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