Tissue disruption treatment and composition for use thereof

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/16 (2006.01) A61P 17/02 (2006.01) A61P 19/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2624316

The present invention relates to an agent having activities in the treatment of a tissue disruption. In particular the invention relates to a composition comprising an effective amount of an active fraction separated from a mixture of plasma and/or serum and at least one metal, metal ion or metal salt thereof, wherein said mixture has been denatured and has an activity selected from one or more of the group consisting of: a) healing tissue disruptions; b) modulating apoptosis; c) modulating the activity of TNF- ; d) modulating the activity of TNF- R; e) modulating the activity of TACE; and f) modulating the activity of a caspase.

La présente invention concerne un agent ayant des activités dans le traitement d'une interruption de tissu. En particulier, l'invention concerne une composition qui comprend une quantité efficace d'une fraction active extraite d'un mélange de sérum et/ou de plasma et d~au moins un métal, un ion de métal ou un sel de métal provenant de celle-ci, où ledit mélange a été dénaturé et possède une des activité sélectionnée parmi: a) guérir des interruptions de tissu ; b) moduler l'apoptose ; c) moduler l'activité du FNT- ; d) moduler l'activité du FNT-R; e) moduler l'activité du TACE ; et f) moduler l'activité d'une caspase.

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