Tissue engineered heart valve

A - Human Necessities – 61 – F

Patent

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Details

A61F 2/24 (2006.01) A61L 27/36 (2006.01) A61L 27/38 (2006.01) C12N 15/02 (2006.01)

Patent

CA 2450683

The tissue-engineered heart valve of the present invention is comprised of elements, such as leaflets, formed from self-supporting human engineered tissue. Such self-supporting tissue is comprised of living biological cells and extracellular matrix without the presence of nonviable scaffolding structures. Thus, the tissue-engineered heart valve of the present invention consists of totally living human tissue which could theoretically function like a native biological structure with the potential to grow, to repair and to remodel.

L'invention concerne une valvule cardiaque faisant appel au génie tissulaire, qui comprend des éléments du type nappes membraneuses. On utilise du tissu humain autoportant pour réaliser ces éléments. Le tissu considéré comporte des cellules biologiques vivantes et une matrice extracellulaire sans structures supports non viables. La valvule résultante est donc constituée de tissu humain entièrement vivant qui pourrait théoriquement fonctionner comme une structure biologique native, avec un potentiel de croissance, de réparation et de remodelage.

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