Tissue engineering devices and methods for luminal organs

A - Human Necessities – 61 – L

Patent

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A61L 27/36 (2006.01)

Patent

CA 2685048

Tissue engineering devices and methods are provided for the reconstruction, repair, augmentation, or replacement of a luminal organ or tissue structure involving the use of a biodegradable polymer matrix conforming to a portion of a laminarly arranged luminal organ, the processing of autologous, allogeneic or xenogeneic tissue comprising multiple cell populations to obtain a minced tissue composition, the seeding of the matrix with the composition, and the implanting of the seeded polymer matrix into a patient.

L'invention concerne des dispositifs et des procédés de manipulation de tissus permettant de reconstruire, de réparer, d'augmenter ou de remplacer un organe à lumière ou une structure tissulaire. Les procédés selon l'invention impliquent l'utilisation d'une matrice de polymère biodégradable se conformant à une partie d'un organe à lumière laminaire, le traitement du tissu autologue, allogène ou xénogène comprenant de multiples populations cellulaires pour obtenir une composition de tissu émincée, l'ensemencement de la matrice avec la composition, et l'implantation de la matrice de polymère ensemencée chez le patient.

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